Hyaluronic acid (HA) occurs naturally in connective tissue, joints, and skin. In equine supplements, it is commonly included in products intended to support joint or digestive health.
What We Know and What We Do Not
We are not aware of strong equine research showing that hyaluronic acid itself reduces magnesium absorption or makes a magnesium supplement less effective. We have heard individual reports from horse owners who noticed a change after adding a gut or joint supplement containing HA, but those observations are anecdotal. They do not establish HA as the cause.
Many combination supplements contain other active ingredients, fibers, binders, herbs, or minerals. Changes in the horse’s diet, workload, health, medications, or feeding schedule may also affect the response an owner observes.
A Practical Way to Evaluate Supplement Changes
- Review the complete labels. Compare every ingredient rather than assuming HA is responsible.
- Change one variable at a time. This makes it easier to tell whether a feeding adjustment affects the horse.
- Keep useful notes. Record doses, feeding times, manure changes, workload, behavior, and any medications.
- Ask for professional guidance. A veterinarian or qualified equine nutritionist can help evaluate the entire ration and determine whether supplements should be separated or adjusted.
Do not discontinue prescribed medications or medically necessary supplements based on a suspected interaction. If your horse’s response to MagRestore changes after a new product is introduced, contact our team and include the complete product labels so we can help you review the feeding program.

